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Rapid enhanced-LAMP (e-LAMP) test v1

Alka Saxena, Muhammad Munir Iqbal

License: CC BY

Abstract: Colorimetric Loop Amplification (LAMP) is a fast diagnostic tool which identifies presence of pathogenic RNA or DNA through a colour change. This method is not used widely because it is not as sensitive as real time PCR (lacks in sensitivity) and the negative control also becomes positive eventually (lacks in specificity). At Genomics WA, have developed a solution e-solution, which increases the sensitivity and specificity of colorimetric LAMP. Use of this solution keeps the negative control negative for a long time, thus enabling low copy numbers of pathogens to be detected. Our solution improves the sensitivity and specificity of colorimetric LAMP.

Published on 08 Sep. 2020